2009Journal of Clinical HematologyRequires access

Practice clinic individual transfusion by detecting Rh blood group antigen

Wenli Zhang

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Abstract

Objective:To choose the matching blood to the clinic RhD negative patients who had irregular antibody by detecting Rh blood group antigen.Method:D antigen,other Rh blood group antigen and irregular antibody of clinic RhD negative patients from January 2007 to December 2008 were detected and analyzed.Result:In 79 cases of RhD negative clinic samples,25 cases were irregular antibody positive,as well as 3 cases of anti-D,8 of anti-E,4 of anti-c,7 of anti-c and E,1 of anti-C and 3 of anti-e.The patients who had irregular antibody all received Rh matched blood transfusion,including 7 patients received the O type RBC transfusion with the phenotype of ccdEE and CCdee.Conclusion:It could avoid irregular antibody formation and adverse transfusion reaction by choosing the Rh matched blood to the patients who had anti-c and anti-e antibody using antibody screening and Rh blood group antigen detection.

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What this paper is about

Objective:To choose the matching blood to the clinic RhD negative patients who had irregular antibody by detecting Rh blood group antigen.Method:D antigen,other Rh blood group antigen and irregular antibody of clinic RhD negative patients from January 2007 to December 2008 were detected and analyzed.Result:In 79 cases of RhD negative clinic samples,25 cases were irregular antibody positive,as well as 3 cases of anti-D,8 of anti-E,4 of anti-c,7 of anti-c and E,1 of anti-C and 3 of anti-e.The patients who had irregular antibody all received Rh matched blood transfusion,including 7 patients received the O type RBC transfusion with the phenotype of ccdEE and CCdee.Conclusion:It could avoid irregular antibody formation and adverse transfusion reaction by choosing the Rh matched blood to the patients who had anti-c and anti-e antibody using antibody screening and Rh blood group antigen detection.

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Available abstract

Objective:To choose the matching blood to the clinic RhD negative patients who had irregular antibody by detecting Rh blood group antigen.Method:D antigen,other Rh blood group antigen and irregular antibody of clinic RhD negative patients from January 2007 to December 2008 were detected and analyzed.Result:In 79 cases of RhD negative clinic samples,25 cases were irregular antibody positive,as well as 3 cases of anti-D,8 of anti-E,4 of anti-c,7 of anti-c and E,1 of anti-C and 3 of anti-e.The patients who had irregular antibody all received Rh matched blood transfusion,including 7 patients received the O type RBC transfusion with the phenotype of ccdEE and CCdee.Conclusion:It could avoid irregular antibody formation and adverse transfusion reaction by choosing the Rh matched blood to the patients who had anti-c and anti-e antibody using antibody screening and Rh blood group antigen detection.

Key concepts: Medicine, Rh blood group system, Antibody, Antigen, Blood transfusion, Blood type (non-human), Blood group antigens, Transfusion reaction

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