ScholarLens Back to search
2004•Zhonghua gan-dan waike zazhiRequires access

Therapeutic effects of reasonable nutrition support on severe acute pancreatitis

Xiong Jiong-xi

Open publisher page 0 citations

Abstract

Objective To investigate the therapeutic effects of reasonable nutrition support on severe acute pancreatitis (SAP). Methods Ninety-six cases of SAP were randomized into 2 groups. Total parenteral nutrition (TPN) was performed in group A and combination of enteral and parenteral nutrition was done in group B. Serum endotoxin,urine L/M,CD4/CD8 and IgG were detected to evaluate permeability of enteral mucosa and immune function,respectively. Meanwhile,serum TNF-α,IL-6,infection rate and mortality were determined. Results CD4/CD8 and IgG were significantly higher but serum endotoxin,urine L/M,serum TNF-α,IL-6,infection rate and mortality markedly lower in group B than in group A (P0.05). Conclusions Reasonable combination of enteral and parenteral nutrition can inhibit release of inflammatory cytokines and media. Therefore,it is suitable for treatment of SAP.

About this research paper

What this paper is about

Objective To investigate the therapeutic effects of reasonable nutrition support on severe acute pancreatitis (SAP). Methods Ninety-six cases of SAP were randomized into 2 groups. Total parenteral nutrition (TPN) was performed in group A and combination of enteral and parenteral nutrition was done in group B. Serum endotoxin,urine L/M,CD4/CD8 and IgG were detected to evaluate permeability of enteral mucosa and immune function,respectively. Meanwhile,serum TNF-α,IL-6,infection rate and mortality were determined. Results CD4/CD8 and IgG were significantly higher but serum endotoxin,urine L/M,serum TNF-α,IL-6,infection rate and mortality markedly lower in group B than in group A (P0.05). Conclusions Reasonable combination of enteral and parenteral nutrition can inhibit release of inflammatory cytokines and media. Therefore,it is suitable for treatment of SAP.

Why it matters

A significance statement is not available in the OpenAlex record.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Objective To investigate the therapeutic effects of reasonable nutrition support on severe acute pancreatitis (SAP). Methods Ninety-six cases of SAP were randomized into 2 groups. Total parenteral nutrition (TPN) was performed in group A and combination of enteral and parenteral nutrition was done in group B. Serum endotoxin,urine L/M,CD4/CD8 and IgG were detected to evaluate permeability of enteral mucosa and immune function,respectively. Meanwhile,serum TNF-α,IL-6,infection rate and mortality were determined. Results CD4/CD8 and IgG were significantly higher but serum endotoxin,urine L/M,serum TNF-α,IL-6,infection rate and mortality markedly lower in group B than in group A (P0.05). Conclusions Reasonable combination of enteral and parenteral nutrition can inhibit release of inflammatory cytokines and media. Therefore,it is suitable for treatment of SAP.

Key concepts: Parenteral nutrition, Acute pancreatitis, Medicine, Gastroenterology, Urine, Internal medicine, Pancreatitis, Therapeutic effect

Related papers

Related paper 1Related paper 2Related paper 3
Back to paper searchBrowse research topicsOriginal source
Therapeutic effects of reasonable nutrition support on severe acute pancreatitis — Research Paper | ScholarLens