Patients with nephropathy serum cystatin C detection clinical application

Objective To investigate the clinical value of serum cystatin C(CysC) leve in patients with kidney disease.Methods From May 2011 to June,80 hospitalized patients with kidney disease were tested about serum CysC level,enzymatic determination of the level of serum creatinine(SCR) by immune turbidimetric method,and 167 healthy subjects were control group.The mean serum CysC level was(2.91±2.09)mg/L and the mean SCR level was(287.26±283.65)μmol/L in kidney disease patients,these were significantly higher than control group with serum CysC level of(0.90±0.24)mg/L and SCR level of(62.63±19.02)μmol/L(P0.05).In kidney diseas group,positive rate of CysC was significantly higher than SCR,but the difference was not statistically significant(P0.05)Results Conclusion Serum CysC in patients with kidney disease has a higher detection rate,it is a good indicator for reflecting kidney disease in patients with renal impairment.