Observation of the reflux characteristics of reflux esophagitis in patients with different body mass indexes using multichannel intraluminal impedance

Objective To observe the reflux characteristics of patients with reflux esophagitis in different body mass indexes using combined multichannel intraluminal impedance-pH(MII-pH) monitoring.Methods 56 patients with reflux esophagitis were enrolled and divided into the normal group,overweight group and obesity group according to their body mass indexes.We observed reflux-related indicators of individuals with MII-pH monitoring,and then performed statistical analysis on pH monitoring and impedance results.Results Compared with normal group,there were significant differences in overweight group and obesity group on percent time pH4(total,upright and recumbent),acid reflux and liquid reflux(P0.05 or 0.01),while no significant differences were found between overweight and obesity groups(all P0.05).There were no significant differences in weakly acid reflux,non-acid reflux,mixed reflux,gas reflux and proximal reflux episodes among the three groups(all P0.05).Conclusion There are more acid exposure,acid reflux and liquid reflux episodes in overweight and obese patients;however,the effect of the extent of obesity on acid exposure,acid reflux and liquid reflux has no significant difference.