The clinical research of radioactive particle stent with iodine-125 seeds in treatment of esophageal cancer

Objective:To observe the clinical application and effect of iodine-125 seeds radioactive particle stent in esophageal cancer.Methods:Forty patients with esophageal cancer were divided into two groups.Group A of twenty patients were treated by radioactive particle stent with iodine-125 seeds;Group B of twenty patients were treated by ordinary esophageal stent.The KPS,complications,dysphagia and survival time of patients were monitored before and after the operation.Results:Two groups of sent installations were very successful.The dysphagia was improved significantly in the two groups after the operation.There were notable differences in statistics between preoperation and postoperation(P0.05),but there were no notable differences in statistics on dysphagia between Group A and Group B after the stent placement(P0.05).KPS of all the patients were improved significantly after stent placement(P0.05),and the KPS was quite different after stent placement in both groups(P0.05).There were no significant differences in complications between the two groups(P0.05).The median survival time was 6.25 months and 4.80 months in group A and group B,respectively.There were significant differences in statistics between the two groups(P0.05).Conclusion:Radioactive particles stent with iodine-125 seeds can mitigate the symptoms of dysphagia and improve the conditions and greatly prolong the survival time of patient,so it has more security to patients and thus is superior to ordinary stent.