Correlation Between ErbB2 Expression and Survival Rates of Osteosarcoma Patients
LU Bia
Abstract
LU Bia
Abstract
Objective:To investigate the expression of ErbB2in patients with osteosarcoma and to determine the relation between ErbB2status and survival rate.Methods:Specimens were collected from 81osteosarcoma patients and immunohistochemical method was used to assay the expression of ErbB2.Results:Of the 81tumors examined,51(61%)demonstrated high levels of ErbB2expression.The presence of increased levels of ErbB2in osteosarcoma was significantly associated with the increased probability of event-free(P0.05)and overall survival(P0.05).Conclusion:In patients with osteosarcoma,ErbB2expression is associated with probability of event-free and overall survival.
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Objective:To investigate the expression of ErbB2in patients with osteosarcoma and to determine the relation between ErbB2status and survival rate.Methods:Specimens were collected from 81osteosarcoma patients and immunohistochemical method was used to assay the expression of ErbB2.Results:Of the 81tumors examined,51(61%)demonstrated high levels of ErbB2expression.The presence of increased levels of ErbB2in osteosarcoma was significantly associated with the increased probability of event-free(P0.05)and overall survival(P0.05).Conclusion:In patients with osteosarcoma,ErbB2expression is associated with probability of event-free and overall survival.
Key concepts: Osteosarcoma, Immunohistochemistry, Overall survival, Correlation, Medicine, Oncology, Internal medicine, Survival analysis