Dynamic study on cardiac troponin-I in the patients with tumor and ischemic heart disease in peri-hyperthermhia-therapy period

Objective To investigate the relationship between the level of cardiac troponin I(cTnI) and the clinical outcome in patients with tumor and ischemic heart disease who are under far-infared hyperthermhia therapy.?Methods 40 cases of ASAⅡ-Ⅲ to be treated by hyperthemrrhia therapy were divided into a cTnI positive and a cTnI negative group with their level of cTnI above and below 0.3 μg/L respectively.The patients′ level of cTnI was monitored dynamically: after anesthesia induction,immediately and 6 h after hyperthermhia therapy.The changes in ECG and the incidence of cardiac event were recorded.?Results The level of cTnI was significently elevated in both groups after the therapy(P0.05 or P0.01).The increment of cTnI level was higher in the positive group than in the negative group(P0.01).The changes in ECG and the incidence of cardiac events were more frequent in the positive group than in the negative group(P0.01).?Conclusion cTnI is a reliable marker for judging the cardial injury.Relatively high basal level of cTnI is of value in screening the high-risk patients.