The use of novel flow diverting device Tubridge for the treatment of intracranial aneurysms: initial experience

Objective To preliminarily evaluate the feasibility,efficacy and safety of the novel flow diverting device,Tubridge,in treating intracranial aneurysms.Methods The novel flow diverting device,Tubridge,was employed to treat intracranial aneurysms in 14 patients with a mean age of(52.4 ± 10.2) years.A total of 14 intracranial aneurysms were detected in 14 patients,including 13 un-ruptured aneurysms and one ruptured aneurysm.The technical results and clinical data were analyzed.Results A total of 18 flow diverters were implanted.The flow diverter was successfully conveyed and delivered in all patients,with a technical success rate of 100%.Six aneurysms were treated with the flow diverter together with the coils.Of the six aneurysms,complete obliteration of the aneurysm was obtained in 2(Raymond grade I),remnant of neck was seen in 1(Raymond grade II) and residual aneurysm sac was found in 3(Raymond grade III) cases.Eight aneurysms were treated with flow diverter implantation alone.After the procedure,marked decrease in contrast filling of the aneurysm sac was seen in 3 aneurysms,while the change in contrast filling pattern of the aneurysm sac as well as the obvious retention of contrast in the aneurysm sac could be detected in all cases.No procedure-related hemorrhagic or ischemic complications occurred.The mRS score at the time of discharge was 0(n = 13) or 1(n = 1).Conclusion For the treatment of some special type intracranial aneurysms,the use of Tubridge flow diverter is clinically feasible,its effect is immediate and satisfactory with higher safety in short term.However,its long-term efficacy and safety need to be further evaluated.