CURATIVE EFFECT OF SEQUENTIAL THERAPY ON PEPTIC ULCER WITH HELICOBACTER PYLORI INFECTION

Objective To evaluate the efficacy of sequential therapy on peptic ulcer with helicobacter pylori infection.Methods 126 patients with peptic ulcer were randomly divided into treating group and control group.All of them were confirmed to be infected with helicobacter pylori by rapid urease test(RUT) and 14C-urea breath test(UBT).The treating group was treated with 10-day sequential therapy and the control group with 10-day standard triple therapy.Results Compared with the control group,the ulcer healing and symptom remission of the treating group had no significant difference;The Hp eradication rate of the treating group was 96.5%,and that of the control group was 75.3%.The difference between the two groups was significant.There was no serious adverse reaction of the two groups.Conclusion Sequential therapy could relieve symptoms,promote ulcer healing and eradicate Hp effectively and safely.