Protective Effect of Continuous Veno-veno Hemofiltration on Patients with Severe Acute Pancreatitis

Objective To explore the protective effect of continuous veno-venous hemofiltration(CVVH)on tissue and organ damage induced by severe acute Pancreatitis(SAP).Methods Thirty-seven SAP patients were randomly divided into CVVH group(n=22)and contract group(n=15).Contract group was treated with conventional therapy.While CVVH group was treated with conventional therapy companied by CVVH.Serum amlyase(AMS)and lipopolyase(Lip),the plasma levels of endotoxin and tumor necrosis factor-a(TNF-a)and interleukin-1β(IL-1β)and C-reative protein(CRP),faecal occult blood test and serum leucocyte were examined.Functions of brain,kidney,liver,heart and pulmonary were observed.Results the protective effect was better in CVVH group than that in normal group(P0.05),The survival rate was higher and the number of hospitalization day decreased in CVVH group than those in normal group.Conclusion CVVH has a significant protection against tissue and organ damage induced by SAP.