Optical coherence tomography measurement of retinal nerve fiber layer after acute primary angle closure glaucoma

Objective To detect retinal nerve fiber layer(RNFL)thickness after acute primary angle closure glaucoma under attack.Methods This is a prospective,observational case study.Thirty-six patients who had a single unilateral APAC attack and 36 single eyes from normal controls were tested by stratus optical coherence tomography(OCT)with circular scans around the optic nerve head(diameter=3.46 mm).Duration of APAC attack was(12.4±8.4)hours.Comparisons of average RNFL thickness and RNFL thickness in four quadrants,and normal controls were made.Results At the time of admission,the RNFL thickness of superior quadrant and inferior quadrant of patients were increased comparing with the controls.After the intraocular pressure has been controlled,the RNFL thickness gradually decreased,and there are significant differences among 1,3,and 6 m.Conclusion Superior quadrant and inferior quadrant RNFL thickness was significantly increased at the time of admission.After the intraocular pressure has been controlled,the RNFL thickness was thinning.