Study on the role of cellular immunity in the pathogenisis of urticaria

Objective To study the function of cellular immunity of patients with urticaria. Methods T-lymphocytes subpopulations of the peripheral blood in 60 patients with rticaria and 40 healthy controls were examined by flow cytometry. Results The number of CD3 + and CD4 + cells in the urticaria group were significantly lower than those in the control group (P0.01), especially in patients with acute urticaria. Conclusion There was immunologic dysfunction of T lymphocyte in the patients with urticaria, and not only humoral immunity but also cellular immunity plays a certain role in the pathogenesis of urticaria.