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Effects of Kumquat Flavonoid Extracts on the Blood Lipid Reduction Of Obese Rats with Hyperlipidemia

Zhonghai Li

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Abstract

Through a determination of the levels of serum total cholesterol(TC),triglycerides(TG) and high-density lipoprotein cholesterol(HDL-C),and the index of low-density lipoprotein cholesterol(LDL-C),in some obese rats with hyperlipidemia,a study was made of the effects of Hunan Liuyang kumquat flavonoid extracts(FC1) and Jiangxi Suichuan ones(FC2) upon blood lipid reduction.The results show that compared with the controlled rats,the serum TG values(P0.05) of obese rats significantly decrease at 80 mg·kg-1 dose by FC1 or FC2 and their values of serum TC and LDL-C(P0.01) are extremely low;that the LDL-C values(P0.05) of the test rats are significantly reduced at the 20 mg·kg-1 dose by FC2 and furthermore,their serum TG values(P0.01) can be significantly lowered by FC1 or FC2 at 160 mg·kg-1 dose;and that the serum TC concentration of the test rats has also been significantly decreased(P0.05).To sum up,the flavonoid extracts in the kumquats can efficiently lower the blood lipid in the obese rats with hyperlipidemia.

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What this paper is about

Through a determination of the levels of serum total cholesterol(TC),triglycerides(TG) and high-density lipoprotein cholesterol(HDL-C),and the index of low-density lipoprotein cholesterol(LDL-C),in some obese rats with hyperlipidemia,a study was made of the effects of Hunan Liuyang kumquat flavonoid extracts(FC1) and Jiangxi Suichuan ones(FC2) upon blood lipid reduction.The results show that compared with the controlled rats,the serum TG values(P0.05) of obese rats significantly decrease at 80 mg·kg-1 dose by FC1 or FC2 and their values of serum TC and LDL-C(P0.01) are extremely low;that the LDL-C values(P0.05) of the test rats are significantly reduced at the 20 mg·kg-1 dose by FC2 and furthermore,their serum TG values(P0.01) can be significantly lowered by FC1 or FC2 at 160 mg·kg-1 dose;and that the serum TC concentration of the test rats has also been significantly decreased(P0.05).To sum up,the flavonoid extracts in the kumquats can efficiently lower the blood lipid in the obese rats with hyperlipidemia.

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Available abstract

Through a determination of the levels of serum total cholesterol(TC),triglycerides(TG) and high-density lipoprotein cholesterol(HDL-C),and the index of low-density lipoprotein cholesterol(LDL-C),in some obese rats with hyperlipidemia,a study was made of the effects of Hunan Liuyang kumquat flavonoid extracts(FC1) and Jiangxi Suichuan ones(FC2) upon blood lipid reduction.The results show that compared with the controlled rats,the serum TG values(P0.05) of obese rats significantly decrease at 80 mg·kg-1 dose by FC1 or FC2 and their values of serum TC and LDL-C(P0.01) are extremely low;that the LDL-C values(P0.05) of the test rats are significantly reduced at the 20 mg·kg-1 dose by FC2 and furthermore,their serum TG values(P0.01) can be significantly lowered by FC1 or FC2 at 160 mg·kg-1 dose;and that the serum TC concentration of the test rats has also been significantly decreased(P0.05).To sum up,the flavonoid extracts in the kumquats can efficiently lower the blood lipid in the obese rats with hyperlipidemia.

Key concepts: Hyperlipidemia, Flavonoid, Blood lipids, Internal medicine, Chemistry, Cholesterol, Endocrinology, Total cholesterol

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Effects of Kumquat Flavonoid Extracts on the Blood Lipid Reduction Of Obese Rats with Hyperlipidemia — Research Paper | ScholarLens