Observation on higher order aberrations of myopia in scotopic environment

Objective: To explore the distribution of ocular high-order aberrations of myopic eyes in scotopic environment,and to indentify the influences of age on the aberrations.Methods:In a scotopic environment,WaveScan(visx.inc.) were applied to examine 140 patients(280 myopic eyes) before they undergoing LASIK surgery,root-mean-square(RMS) values and Zernike coefficients were analyzed when pupil size were dilated to be 6.0 mm.The patients were divided into different groups according to refractive power and age.Results: In a scotopic environment,mean RMS value was(0.251±0.089) μm showing a decreasing tendency from 3rd to 6th order aberrations.Among the aberrations,3rd-order coma,trefoil and 4th-order spherical aberration were the most significant ones.High order aberrations increased with the refractive power.Significant differences were found among myopia,total ocular high order RMS and coma(P all 0.05).RMS of 3rd coma and trefoil increased with age.Conclusions: High-order aberrations varied widely among individuals.The RMS values decreased from 3rd to 6th order.Among the aberrations,the most significant ones were 3rd coma,trefiol and 4th spherical aberration.High-order aberrations increased with refractive power,while 3rd coma and trefoil increased with age.