2004•Journal of Science of Teachers' College and UniversityRequires access

RNAi mechanism and application

Bo Fu, Shu‐Li Shao

Abstract

RNAi means gene silencing triggered by double-stranded RNA. Through the study of flies, bugs, fungi and plants, the mechanism of RNAi has been confirmed. The key player in RNAi is small interference RNA(siRNA) generated by Dicer. Now more and more evidences show that application of RNAi plays an important role in biotechnology and will be useful for treating human genetic disease.

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Available abstract

Key concepts: RNA interference, Dicer, RNA silencing, Gene silencing, Biology, Mechanism (biology), Gene, Genetics