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Mirtazapine Compared with Paroxetine in Depressed Patients with Anxiety Symptoms

Tang Zhen

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Abstract

Objective:To compare the efficacy of mirtazapine with that of paroxetine.Methods:60 patients with a diagnosis of major depressive episode(CCMD-3)were randomly assigned to 6 weeks of treatment with mirtazapine or paroxetine.Efficacy was assessed with HAM-D-17 at the end of baseline and 1,2,4,6 weeks after treatment.Results:Both medications had comparable efficacy.Mirtazapine responded more quickly and showed significant improvement of anxiety symptoms at the beginning of the treatment.Conclusion:mirtazapine had good effectiveness in the depressed patients with anxiety symptoms.

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What this paper is about

Objective:To compare the efficacy of mirtazapine with that of paroxetine.Methods:60 patients with a diagnosis of major depressive episode(CCMD-3)were randomly assigned to 6 weeks of treatment with mirtazapine or paroxetine.Efficacy was assessed with HAM-D-17 at the end of baseline and 1,2,4,6 weeks after treatment.Results:Both medications had comparable efficacy.Mirtazapine responded more quickly and showed significant improvement of anxiety symptoms at the beginning of the treatment.Conclusion:mirtazapine had good effectiveness in the depressed patients with anxiety symptoms.

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Available abstract

Objective:To compare the efficacy of mirtazapine with that of paroxetine.Methods:60 patients with a diagnosis of major depressive episode(CCMD-3)were randomly assigned to 6 weeks of treatment with mirtazapine or paroxetine.Efficacy was assessed with HAM-D-17 at the end of baseline and 1,2,4,6 weeks after treatment.Results:Both medications had comparable efficacy.Mirtazapine responded more quickly and showed significant improvement of anxiety symptoms at the beginning of the treatment.Conclusion:mirtazapine had good effectiveness in the depressed patients with anxiety symptoms.

Key concepts: Mirtazapine, Paroxetine, Anxiety, Psychology, Psychiatry, Depressive symptoms, Medicine, Antidepressant

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