2013•Zhonghua zhongyiyao xuekanRequires access

Study on Chemical Constituents of Peristrophe baphica

XU Qiping

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Abstract

Objective:To investigate chemical constituents of Peristrophe baphica(Spreng)Bremek.Methods:The chemical constituents were isolated and purified with silica gel and Sephadex LH-20 column chromatography.Their structures were identified by spectral data and physicochemical properties.Results:Seven chemical constituents were isolated and identified as 6,7-methylenedioxy-5,8-dimethoxy coumarin(1),4,6,7-trimethoxy-5-methyl coumarin(2),6,7-dihydroxycomnarin(3),3,4-dihydroxy benzoic acid(4),isovanillic acid(5),daucosterol(6) and β-sitosterol(7),respectively,from the EtOAc fraction of EtOH extract of P.baphica.Conclusions:All the compounds except 6 and 7 were obtained from P.baphica for the first time.

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Objective:To investigate chemical constituents of Peristrophe baphica(Spreng)Bremek.Methods:The chemical constituents were isolated and purified with silica gel and Sephadex LH-20 column chromatography.Their structures were identified by spectral data and physicochemical properties.Results:Seven chemical constituents were isolated and identified as 6,7-methylenedioxy-5,8-dimethoxy coumarin(1),4,6,7-trimethoxy-5-methyl coumarin(2),6,7-dihydroxycomnarin(3),3,4-dihydroxy benzoic acid(4),isovanillic acid(5),daucosterol(6) and β-sitosterol(7),respectively,from the EtOAc fraction of EtOH extract of P.baphica.Conclusions:All the compounds except 6 and 7 were obtained from P.baphica for the first time.

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Available abstract

Objective:To investigate chemical constituents of Peristrophe baphica(Spreng)Bremek.Methods:The chemical constituents were isolated and purified with silica gel and Sephadex LH-20 column chromatography.Their structures were identified by spectral data and physicochemical properties.Results:Seven chemical constituents were isolated and identified as 6,7-methylenedioxy-5,8-dimethoxy coumarin(1),4,6,7-trimethoxy-5-methyl coumarin(2),6,7-dihydroxycomnarin(3),3,4-dihydroxy benzoic acid(4),isovanillic acid(5),daucosterol(6) and β-sitosterol(7),respectively,from the EtOAc fraction of EtOH extract of P.baphica.Conclusions:All the compounds except 6 and 7 were obtained from P.baphica for the first time.

Key concepts: Daucosterol, Coumarin, Chemistry, Sephadex, Chemical constituents, Chromatography, Silica gel, Column chromatography

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