Evaluation on the Clinical Efficacy of Intracavitary Brachytherapy Combined with External Beam Radiotherapy in Controlling Postoperative Recurrence of Oral Cancer

Objective To explore clinical efficacy and value of intracavitary brachytherapy combined with external beam radiotherapy in controlling postoperative recurrence of oral cancer. Methods A total of60 patients diagnosed as postoperative recurrence of oral cancer in Department of Stomatology,Shunde First People's Hospital from Mar. 2003 to Mar. 2013 were divided into two groups according to random number table,with 30 cases in each group. Patients in the combined group were given60 Co γ conventional external beam radiotherapy and intracavitary radiotherapy as supplement,and supplement dose of reference point was5 mm submucosal,10 Gy per time,2-3 times,interval of 3 days. Patients in the conventional group received only conventional external beam radiotherapy. Lesion changes,local control rate and distant metastasis rate and other indicators of the two groups before and after the treatment were observed and compared. Results Intracavitary brachytherapy combined with external beam radiotherapy improved the local lesion and the local control rate in patients with recurrence of oral cancer( P 0. 05). Distant metastasis rate of the two groups had no statistically significant difference( P 0. 05). Conclusion Relying on mature technological conditions,intracavitary brachytherapy combined with external beam radiotherapy can significantly improve the local lesions,prolong the survival time,and improve the quality of life in patients with postoperative recurrence of oral cancer,without causing serious complications.