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2004•Guangdong Pharmaceutical JournalRequires access

Determination of dissolution of diclofenac sodium enteric-coated tablets

Huang Guan-liang

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Abstract

Objective To establish a method for determination of dissolution of diclofenac sodium enteric-coated tablets. Methods Determination of dissolution of diclofenac sodium enteric-coated tablets by UV method.Results The linear range was 6.0～20.0 μg/ml,r = 0.9998;the average recoveries was 99.8%, RSD=0.3% (n=9) .Conclusion The method is simple, accurate ,which may be a suitable method for determination of dissolution of diclofenac sodium enteric-coated tablets.

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What this paper is about

Objective To establish a method for determination of dissolution of diclofenac sodium enteric-coated tablets. Methods Determination of dissolution of diclofenac sodium enteric-coated tablets by UV method.Results The linear range was 6.0～20.0 μg/ml,r = 0.9998;the average recoveries was 99.8%, RSD=0.3% (n=9) .Conclusion The method is simple, accurate ,which may be a suitable method for determination of dissolution of diclofenac sodium enteric-coated tablets.

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Available abstract

Objective To establish a method for determination of dissolution of diclofenac sodium enteric-coated tablets. Methods Determination of dissolution of diclofenac sodium enteric-coated tablets by UV method.Results The linear range was 6.0～20.0 μg/ml,r = 0.9998;the average recoveries was 99.8%, RSD=0.3% (n=9) .Conclusion The method is simple, accurate ,which may be a suitable method for determination of dissolution of diclofenac sodium enteric-coated tablets.

Key concepts: Diclofenac Sodium, Enteric coated, Dissolution, Chromatography, Diclofenac, Dissolution testing, Chemistry, Sodium

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