Predictive Factors of Gastrointestinal Bleeding in Acute Intracerebral Hemorrhage:a Clinical Retrospective Study

Objectives To evaluate the frequency,severity,predictive factors for gastrointestinal(GI) hemorrhage in patients with acute intracerebral hemorrhage.Methods One hundred and twenty five patients with acute intracerebral hemorrhage(ICH) were included in a retrospective case-control study.The occurrence of GI hemorrhage was the variable of outcome.Some clinical parameters were evaluated by univariate followed by multivariate logistic regression analysis.Results On univariate analysis,age,GCS,pupillary asymmetry,mean BP,serum glucose,intraventricular hemorrhage(IVH),hematoma with a size,mass effect,hydrocephalus,prothrombin time and hematoma evacuation significantly correlated with GI hemorrhage.On multivariate analysis,the independent predictors of GI hemorrhage included low GCS(P0.001),hematoma with size beyond 30 ml(P=0.017),IVH(P=0.018) and hematoma evacuation(P=0.043).Conclusion Low GCS,larger hematoma,IVH and operation wound are the important predictors for GI hemorrhage in acute ICH.