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Study on Synthesis and Fungicidal Activity of 1H-Indene-2-carboxylic Derivatives

Han Kui-yuan

Abstract

Ten novel 1H-indene-2-carboxylic derivatives with enamine structure were synthesized and confirmed with 1H NMR and MS spectra.The preliminary fungicidal activity results showed that the title compounds exhibited certain fungicidal activities.For example,the compound 6h showed 87.9% and 93.0% fungicidal activity against Sclerotonia sclerotiorum and Botrytis cinerea,respectively,at 25 mg/L.

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Key concepts: Chemistry, Botrytis cinerea, Fungicide, Indene, Enamine, Proton NMR, Organic chemistry, Medicinal chemistry