Follow up and analysis of percutaneous radiofrequency ablation on malignant hepatic carcinoma

Objective To analyze the effectiveness of percutaneous radiofrequency ablation for patients with malignant hepatic carcinoma. Methods Between Jun. 2007 to Jul. 2008,29 patients with malignant hepatic carcinoma were treated with percutaneous radiofrequency ablation (Medsphere S-1500). The authors prospectively analyzed hepatic function and followed up of imaging examination. Results CR was attained in 79.3%(23/29) patients. PR was attained in 13.8%(4/29) patients. NC was attained in 3.4% (1/29) patients. PD was attained in 3.4% (1/29) patients. The 3,6,12,18 month survival rates were 96%,96%,92%,58% respectively. The percutaneous radiofrequency ablation did not have significant effects on Child-Pugh score. Conclusion Percutaneous radiofrequency ablation with Medsphere S-1500 guided by CT is an effective method for malignant hepatic carcinoma less than 5cm in diameter. The risk of complication is low,and it has no significant effects on liver function. The further studies are necessary for us to focus on long-term outcomes.