2009Unpublished venueRequires access

Clinical application of magnetic resonance diffusion tensor imaging for spinal cord injury diagnosis

Chen Yan-jie

Open publisher page 0 citations

Abstract

Objective:To investigate the clinical application of magnetic resonance(MR)diffusion tensor imaging for spinal cord injury diagnosis.Methods:Conventional cervical magnetic resonance imaging(MRI)scanning and MR diffusion tensor imaging were performed on 54 patients with cervical spondylotic myelopathy and 42 cases of healthy volunteers as a healthy control group.Apparent diffusion coefficient(ADC)and fractional anisotropy(FA)were measured,diffusion tensor tracking(DTT)was showed in each group.Results:The average ADC value is(830.34±215.86)×106 mm2/s,the average FA value is(536.03±40.00)×10-3 in control group;in contrast the average ADC value is(1 107.60±47.55)×106 mm2/s,higher than the control group with statistical significant difference(P0.01),and the average FA value is(425.91 ±59.48)×10-3,lower than the control group with statistical significant difference(P0.01).Conclusion:MR diffusion tensor imaging can show the injury in the spinal cord at earlier stage.ADC value,FA value and DTT are sensitive indicators of the early detection of micro-structure of spinal cord injury.

About this research paper

What this paper is about

Objective:To investigate the clinical application of magnetic resonance(MR)diffusion tensor imaging for spinal cord injury diagnosis.Methods:Conventional cervical magnetic resonance imaging(MRI)scanning and MR diffusion tensor imaging were performed on 54 patients with cervical spondylotic myelopathy and 42 cases of healthy volunteers as a healthy control group.Apparent diffusion coefficient(ADC)and fractional anisotropy(FA)were measured,diffusion tensor tracking(DTT)was showed in each group.Results:The average ADC value is(830.34±215.86)×106 mm2/s,the average FA value is(536.03±40.00)×10-3 in control group;in contrast the average ADC value is(1 107.60±47.55)×106 mm2/s,higher than the control group with statistical significant difference(P0.01),and the average FA value is(425.91 ±59.48)×10-3,lower than the control group with statistical significant difference(P0.01).Conclusion:MR diffusion tensor imaging can show the injury in the spinal cord at earlier stage.ADC value,FA value and DTT are sensitive indicators of the early detection of micro-structure of spinal cord injury.

Why it matters

A significance statement is not available in the OpenAlex record.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Objective:To investigate the clinical application of magnetic resonance(MR)diffusion tensor imaging for spinal cord injury diagnosis.Methods:Conventional cervical magnetic resonance imaging(MRI)scanning and MR diffusion tensor imaging were performed on 54 patients with cervical spondylotic myelopathy and 42 cases of healthy volunteers as a healthy control group.Apparent diffusion coefficient(ADC)and fractional anisotropy(FA)were measured,diffusion tensor tracking(DTT)was showed in each group.Results:The average ADC value is(830.34±215.86)×106 mm2/s,the average FA value is(536.03±40.00)×10-3 in control group;in contrast the average ADC value is(1 107.60±47.55)×106 mm2/s,higher than the control group with statistical significant difference(P0.01),and the average FA value is(425.91 ±59.48)×10-3,lower than the control group with statistical significant difference(P0.01).Conclusion:MR diffusion tensor imaging can show the injury in the spinal cord at earlier stage.ADC value,FA value and DTT are sensitive indicators of the early detection of micro-structure of spinal cord injury.

Key concepts: Medicine, Diffusion MRI, Fractional anisotropy, Magnetic resonance imaging, Effective diffusion coefficient, Spinal cord, Nuclear medicine, Spinal cord injury

Related papers

Back to paper searchBrowse research topicsOriginal source
Clinical application of magnetic resonance diffusion tensor imaging for spinal cord injury diagnosis — Research Paper | ScholarLens