Observation of Anti-epileptic Behavior on Catgut Implantation at Acupoint in Epilepsy Rats Induced by Penicilin
Peng Chu-xiang
Abstract
Peng Chu-xiang
Abstract
Objective To study the effects of catgut implantation at acupoint on epileptic attack behavior in experimental epilepsy rats. Methods 40 rats were randomly divided into model group, catgut implantation group, western medicine group and acupuncture group. Making the acute epilepsy model by intraperitoneal injection of penicilin in rats after pretreatment, observed the latent period and the performance of epilepsy seizures within 70 minutes after intraperitoneal injection of penicilin. Results The latent period of catgut implantation, western medicine and acupuncture groups was prolonger than model group (P 0.05 or P 0.01), but there was not statistical significance among the three groups (P 0.05). The times of epileptic attack behavior in catgut implantation group including nodding/tail-flick, beard shaking, anterior/hind limb tic, systemic tic and jump was less than the model group respectively (P 0.05 or P 0.01), and the whole seizure level was less than model group too (P 0.05). Conclusion Catgut implantation at acupoint could prolong the latent period of epilepsy seizures, diminish the symptom and level of epilepsy attack, and have conspicuous anti-epilepsy effect.
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Objective To study the effects of catgut implantation at acupoint on epileptic attack behavior in experimental epilepsy rats. Methods 40 rats were randomly divided into model group, catgut implantation group, western medicine group and acupuncture group. Making the acute epilepsy model by intraperitoneal injection of penicilin in rats after pretreatment, observed the latent period and the performance of epilepsy seizures within 70 minutes after intraperitoneal injection of penicilin. Results The latent period of catgut implantation, western medicine and acupuncture groups was prolonger than model group (P 0.05 or P 0.01), but there was not statistical significance among the three groups (P 0.05). The times of epileptic attack behavior in catgut implantation group including nodding/tail-flick, beard shaking, anterior/hind limb tic, systemic tic and jump was less than the model group respectively (P 0.05 or P 0.01), and the whole seizure level was less than model group too (P 0.05). Conclusion Catgut implantation at acupoint could prolong the latent period of epilepsy seizures, diminish the symptom and level of epilepsy attack, and have conspicuous anti-epilepsy effect.
Key concepts: Epilepsy, Medicine, Acupuncture, Intraperitoneal injection, Western medicine, Anesthesia, Animal model, Rat model