Assessment of local function of left ventricle in hypertrophic cardiomyopathy with Doppler tissue imaging

Objective To assess local function of left ventricle in patients with hypertrophic cardiomyopathy by Doppler tissue imaging. Methods The systolic and diastolic peak velocities of ventricular septal and posterior wall of left ventricle were measured in 76 patients with hypertrophic cardiomyopathy and 50 normal volunteers by Doppler tissue imaging, respectively. The variables were determined with the use of statistic analysis.Results Compared with control group, systolic peak myocardial velocity and ratio of early diastolic peak velocity to late diastolic peak velocity(Em/Am) were lower in ventricular septal and posterior wall of left ventricle along long axis and Em/Am along short axis were also lower. Conclusions Systolic and diastolic function of sphincter muscle was reduced in ventricular septal and posterior wall of patients with hypertrophic cardiomyopathy. And diastolic function of windstick muscle was also reduced.