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Relationship between Maternal Serum IL-6 and IL-10 Levelsand Preterm Labor with Chorioamnionitis

Zeng Wei-yue

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Abstract

Objective:To investigate the change of maternal serum interleukin-6 and interleukin-10 levels in preterm labor with chorioamnionitis,and to study the effect of IL-6 on monitoring preterm labor with chorioamnionitis and the function of IL-10 in the mechanism of maternal-fetal immune tolerance.Methods:Serum levels of IL-6 and IL-10 in 29 cases of preterm labor and 15 cases of normal term labor were measured by enzyme-linked immunosorbent assay.The partial placenta were detected after labor.Results:The level of serum IL-6 in preterm labor with chorioamnionitis was significantly higher than that of without chorioamnionitis and term labor.(P0.05).The lefel of IL-10 in preterm labor without chorioamnionitis was significantly higher than that of term labor,(P0.05).Conclusion:Maternal serum IL-6 is a useful marker for detection of preterm labor with intrauterine infection,and IL-10 may plays an important role in remain normal pregnancy.

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What this paper is about

Objective:To investigate the change of maternal serum interleukin-6 and interleukin-10 levels in preterm labor with chorioamnionitis,and to study the effect of IL-6 on monitoring preterm labor with chorioamnionitis and the function of IL-10 in the mechanism of maternal-fetal immune tolerance.Methods:Serum levels of IL-6 and IL-10 in 29 cases of preterm labor and 15 cases of normal term labor were measured by enzyme-linked immunosorbent assay.The partial placenta were detected after labor.Results:The level of serum IL-6 in preterm labor with chorioamnionitis was significantly higher than that of without chorioamnionitis and term labor.(P0.05).The lefel of IL-10 in preterm labor without chorioamnionitis was significantly higher than that of term labor,(P0.05).Conclusion:Maternal serum IL-6 is a useful marker for detection of preterm labor with intrauterine infection,and IL-10 may plays an important role in remain normal pregnancy.

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Available abstract

Objective:To investigate the change of maternal serum interleukin-6 and interleukin-10 levels in preterm labor with chorioamnionitis,and to study the effect of IL-6 on monitoring preterm labor with chorioamnionitis and the function of IL-10 in the mechanism of maternal-fetal immune tolerance.Methods:Serum levels of IL-6 and IL-10 in 29 cases of preterm labor and 15 cases of normal term labor were measured by enzyme-linked immunosorbent assay.The partial placenta were detected after labor.Results:The level of serum IL-6 in preterm labor with chorioamnionitis was significantly higher than that of without chorioamnionitis and term labor.(P0.05).The lefel of IL-10 in preterm labor without chorioamnionitis was significantly higher than that of term labor,(P0.05).Conclusion:Maternal serum IL-6 is a useful marker for detection of preterm labor with intrauterine infection,and IL-10 may plays an important role in remain normal pregnancy.

Key concepts: Chorioamnionitis, Medicine, Preterm labor, Placenta, Obstetrics, Pregnancy, Fetus, Biology

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Relationship between Maternal Serum IL-6 and IL-10 Levelsand Preterm Labor with Chorioamnionitis — Research Paper | ScholarLens