Small renal cell carcinoma (report of 76 cases)

Objective To investigate the association of prognosis with clinical features,tumor imaging,and pathological grading and staging in small renal cell carcinoma(SRCC). Methods The clinical data of 76 cases of SRCC (no more than 3 cm in diameter) were analyzed retrospectively.According to the clinical symptoms,they were divided into two groups,symptomatic (hematuria and lumbago) group (n=17,accounting for 22.4%) and asymptomatic group (n=59,77.6%).All the 76 cases underwent CT scan,with the diagnosis rate of 94.7%;69 cases underwent B-ultrasound examination with the diagnosis rate of 84.1%. Results All the 76 cases underwent radical nephrectomy through oblique incision in the lumbus.The excised tumors were pathologically confirmed to be clear cell carcinoma.The patients were followed up for 32 to 87 months(mean,62.7 months).The 1-,3-,and 5-year cancer-free survival rates of the symptomatic and asymptomatic groups were 100% and 53.3%,33.3% and 100%,90.6% and 77.4%,respectively.There were statistically significant differences between the two groups in the 3- and 5-year cancer-free survival rates (P0.05). Conclusions The early diagnosis of small renal cell carcinoma mainly depends on imaging examination such as B-ultrasound and (or) CT scan.The long-term cancer-free survival rate of asymptomatic patients is significantly higher than that of symptomatic patients.