Immunoenhancing Activity of Mactra chinensis Meat Extract in Mice

Objective: To observe the immunoregulatory effect of Mactra chinensis meat extract(EMC, containing 19.01 g of polysaccharide, 1.25 g of taurine and 0.65 g of choline /100 g) in mice. Methods: Mice were orally administered with EMC at doses of 0.5, 1.5, 3.0 g/(kg · d) for 10 d. A series of immune function indices such as the total number and classification of white blood cells(WBC), the titer of antibody production in agglutination reaction and the quantity of plaque-forming cells(PFC), macrophage phagocytosis test, and the weight of body and immune organs were analyzed. Results: Compared with the control group, the relative number of lymphocytes, the activity of antibody production, the quantity of antibody-forming cells, the phagocytic function of mouse peritoneal macrophages and the index of spleen in all the treated groups were improved significantly( P 0.05). Conclusion: EMC enhances the immune activity of normal mice effectively.