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2011•Practical Journal of Clinical MedicineRequires access

Application of antiemetic Granisetron during cancer chemotherapy

Li Zhao

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Abstract

Objective To study the best medication time to inject Granisetron as antiemetic during cancer chemotherapy.Methods Ninety-nine cases of lung cancer patients were randomized into three groups,group A,group B and group C.Group A,B and C were intravenously injected 3 mg of Granisetron 10,30 and 60 minutes before chemotherapy respectively.The symptom of nausea and vomiting was observed after intravenous injection for 7 days.Results The antiemetic effect of group B was significantly superior to that of group A and group C(P0.01).Conclusion Application of Granisetron 30 minutes before chemotherapy has the best antiemetic effect.

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What this paper is about

Objective To study the best medication time to inject Granisetron as antiemetic during cancer chemotherapy.Methods Ninety-nine cases of lung cancer patients were randomized into three groups,group A,group B and group C.Group A,B and C were intravenously injected 3 mg of Granisetron 10,30 and 60 minutes before chemotherapy respectively.The symptom of nausea and vomiting was observed after intravenous injection for 7 days.Results The antiemetic effect of group B was significantly superior to that of group A and group C(P0.01).Conclusion Application of Granisetron 30 minutes before chemotherapy has the best antiemetic effect.

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Available abstract

Objective To study the best medication time to inject Granisetron as antiemetic during cancer chemotherapy.Methods Ninety-nine cases of lung cancer patients were randomized into three groups,group A,group B and group C.Group A,B and C were intravenously injected 3 mg of Granisetron 10,30 and 60 minutes before chemotherapy respectively.The symptom of nausea and vomiting was observed after intravenous injection for 7 days.Results The antiemetic effect of group B was significantly superior to that of group A and group C(P0.01).Conclusion Application of Granisetron 30 minutes before chemotherapy has the best antiemetic effect.

Key concepts: Granisetron, Medicine, Antiemetic, Nausea, Vomiting, Chemotherapy, Anesthesia, Group B

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