Evaluation of Liver Perfusion in Cirrhosis Patients with Projects of Maximum Slope Method on Computed Tomography

Objective To evaluate the accuracy of measuring hepatic perfusion parameters in patients with liver cirrhosis associated with splenomegaly with different maximum slope methods on computed tomography. Materials and Methods CT perfusion was performed in 17 patients with liver cirrhosis associated with splenomegaly and 14 volunteers. Hepatic perfusion parameters were measured with classic maximum slope method, improved project and deconvolution technique respectively. Results In the control group, there was no significant difference in hepatic perfusion between three methods (P0.05). In the liver cirrhosis group, the parameters of portal vein perfusion and total hepatic perfusion calculated by the classic method were significantly lower than other two methods (P0.05). ConclusionIn patients with liver cirrhosis associated with splenomegaly, the improved project was more accurate than the classic method in the evaluation of hepatic perfusion.