Assessment of regional rotation by velocity vector imaging in canine with myocardial ischemia and acute myocardial infarction

Objective To assess the regional rotation in canine with myocardial ischemia and acute myocardial infarction by velocity vector imaging(VVI). Methods Myocardial ischemia and infarction model were successfully made by partly and fully ligating the left anterior descending coronary artery (LAD) in twelve mongrel dogs. The ventricle rotation and strain were measured by VVI. Results The results revealed:The LAD part ligation:rotation decreased in ventricular septal before LAD ligation status in LAD part ligation status(P0.05). The strain and strain rate has no significant difference. The LAD ful ligation:the rotation rate,rotation,circumferential strain and strain rate of the anterior septal,anterior wall and ventricular septal were significantly decreased in myocardial infarction status compared with those in the normal status,and were also significantly decreased compared with those in the myocardial ischemia status(P0.05). The strain and strain rate in the anterior septal,anterior wall and ventricular septal were significantly decreased in myocardial infarction status compared with those in the normal status(P0.05),but not significantly decreased compared with those in partly ligation status. Conclusion VVI can non-invasively and sensitively assess the left ventricular rotation and the results indicated the ventricular rotation is more sensitive than the strain and strain rate in evaluation of the ventricular systolic function.