Analysis of 1 781 Outpatient Antibiotic Prescriptions in Our Hospital

OBJECTIVE:To provide reference for scientific management rational use of antibiotic drugs.METHODS:12 924 outpatient prescriptions were randomly selected from Apr.to Oct.in 2012 according to Prescription Management and Management and Regulation for Hospital Prescription Comment(trials).The utilization of antibiotics was analyzed statistically,and the suggestions were provided the existing problems.RESULTS:Among 12 924 prescriptions,there were 1 781 antibiotic prescriptions(13.78%).There were 128 combined use of antibiotic prescriptions,taking up 1.1% in all antibiotic prescriptions.The prescriptions of Antibiotic for injection took up 3.18% of all antibiotic prescriptions.The frequency of cephalosporins(53.64%) was the highest among all the prescribed antibiotics.Quinolones and macrolides also occupied the 3th,5th position,taking up 11.37% and 9.22% respectively.The frequency of essential antibiotics took up 19.25%,and essential antibiotic prescriptions took up 29.20% averagely.National essential drugs among nitroimidazoles,quinolones and penicillins were far more frequently prescribed than cephalosporins and macrolides.The DDDs of antibiotics in obseterics/gynecology department and ENT department was the highest,accounting for 25.10% and 25.49%,respectively.The irrational antibiotics prescription accounted for 9.43% of all antibiotics in our hospital.CONCLUSIONS:The use of antibiotics is rational basically in outpatient prescription,but more work must be done to ensure that medicines are used safely,effectively and economically in patients.Nitroimidazoles,quinolones and penicillins in the national essential drug list are able to meet the need of large-scale third-grade class A hospitals,but cephalosporins can not.