Distribution and Drug Resistance of Pathogenic Bacteria in Urinary Tract Infection

Objective To analyze the distribution and drug resistance of the common pathogenic bacteria in urinary tract infection so as to provide scientific reference for clinical reasonable use of antibacterial agents. Methods The identification of bacteria and antibacterial sensitivity tests of the isolates were performed by VITEK 2 compact measurement system. Results Gram- negative bacilli were the major pathogenic bacteria in urinary tract infection, accounted for 77.78%(455 strains), of which Escherichia coli and Klebsiella pneumoniae accounted for 41.88%(372 strains)and 14.53%(85 strains), respectively.Drug resistances of Escherichia coli to 18 antibacterial agents showed different. The resistance rates of Escherichia coli to imipenem, ertapenem, amikacin, cefotetan, ampicillin- sulbactam, ciprofloxacin, and piperacillin/ tazobactam were the lowest, which were 4.90%, 6.12%, 6.53%, 6.94%, 7.10%, 7.84%, and 8.57%, respectively. Conclusions Escherichia coli is the main pathogenic bacterium causing urinary tract infection. The pathogenic bacteria of urinary tract infection show significantly different drug resistance. Clinicians should reasonably use antibacterial agents based on the results of clinical laboratory tests so as to reduce the drug resistance of bacteria.