Clinical Significance of Multi-slice CT in Diagnosis of Thyroid Nodules with Calcification

Objective To investigate the clinical significance of features of thyroid nodule with calcification in diagnosis and differential diagnosis of benign and malignant thyroid nodules.Methods We retrospectively analyzed the pathologic results and multi-slice CT(MSCT) signs of 77 cases of thyroid nodules.Results The detection rate of thyroid nodules with calcification in MSCT imaging was 21.60%(35/162),the detection rate of benign nodules was 15.45%(19/123) which was significantly lower than 41.03%(16/39) of malignant nodules.The thyroid calcification ratio of bulky-calcification in benign nodules was higher than that of malignant nodules,while micro-calcification in malignant nodules was higher than that in benign nodules(P0.05).But there was no significant correlation between the number of calcification and malignant nodules.Conclusions Thyroid nodules with calcification especially micro-calcification is considered to be the important sign of thyroid carcinoma.