Coagulation factor and traumatic hemostasis

Coagulation factors,which are involved in the intrinsic and extrinsic coagulation process of organism,perform mutual coordination with the anticoagulation system. The dynamic balance between them inorder to maintain the normal blood physiological state. The molecular structure,physicochemical properties,physiological function involved in the traumatic bleeding hemostasis were detailed in this paper. Meanwhile,the importance of coagulation factors for trauma hemostasis and coagulation,the coagulation factor products,and their use were reviewed here to provide reference for the development of coagulation factors as drugs.