Studies on Sufentanil Combined with Ropivacaine for Delivery Analgesia from Latent Period

Objective To evaluate the effect and feasibility of patient-controlled epidural analgesia(PCEA) for delivery analgesia with sufentanil combined with low ropivacaine in latent period of labor. Methods Ninety primipara were randomly divided into three groups of 30 each, groupⅠ received PCEA when cervical dilatation reached 1 cm, groupⅡ received PCEA when cervical dilatation reached 3 cm, and groupⅢ received no analgesia. Maternal visual analogue scale(VAS), labor, blood loss, drug consumption, side effects of analgesia, and Apgar scores of neonate were studied. Results ①VAS of groupⅠwas lower than those of group Ⅱ and Ⅲ when the cervical dilatation reached 2 and 3 cm in latent period(P0.05).In the active and expulsive stage, the VAS sores of groupⅠand Ⅱ were lower than those of group Ⅲ(P0.05). ②There was no significant difference in maternal blood loss and neonatal Apgar scores(P0.05). The drug consumption of groupⅠwas (38.30±0.63)ml, had no significant difference with (34.25±10.24)ml of group Ⅱ(P0.05). Conclusion Patient-controlled epidural analgesia for delivery analgesia with sufentanil combined with low ropivacaine from latent period of first stage in labor is feasibility, with no obvious side effect on neonate and parturient.