An Analysis of The Catheterization Paths in Regional Artery-perfusion Chemotherapy for 22 Cases with Unresectable Pancreatic Cancer

To investigate the effects of catheterization paths in regional artery-perfusion chemotherapy for 22 cases with unresectable pancreatic cancer. Of the 22 cases with unresectable pancreatic cancer, 8 cases received catheterization chemotherapy with perfusion into the regional pancreatic arteries via the gastroduodenal artery with ligation of the right gastroepiploic artery and the inferior pancreaticoduodenal artery; 10 cases received catheterization via right gastroepiploic artery with ligation of the gastroduodenal artery root; 4 cases received catheterization conversely into the celiac trunk artery via the left gastric artery. No operative death and postoperative complications occurred. Of the 17 cases with pain, 12 cases demonstrated relief, among whom 7 cases with catheterization via the right gastroepiploic artery(7/12). According to the Objective Evaluation Standard of Tumor Treatment(WHO), there were 8 cases with partial response(PR), of whom 4 cases with catheterization via the right gastroepiploic artery(50%), 10 cases with no change(NC) and 4 cases with progressive disease(PD). The average postoperative life span was 12.4 months. [Conclusion] Regional artery-perfusion chemotherapy is proved to be one of the effective methods for pancreatic carcinoma. It is effective for inhibition of malignant growths short term, pain relief, and improving quality of life. The combination of catheterization via the right gastroepiploic artery with ligation of the gastroduodenal artery root is proved of good results.