Effect of Different Concentrations of Hydrogen Peroxide on Hemoglobin Release of Erythrocytes
Wei Chun-hu
Abstract
Wei Chun-hu
Abstract
In order to study the effect of hydrogen peroxide(H2O2)on the hemoglobin release of normal human red blood cell(RBC),The malondialdehyde contents and relative solubility of RBC and hemoglobin release test(HRT)were used to study the hemoglobin release of normal RBCs treated with different concentration(8%,4%,2%,1%,0.5%,0.25%and 0.125%)of H2O2.The results show that the hemoglobin release was increased with increased concentration of H2O2.However,high concentration of H2O2could decrease the released Hb.So different concentrations of H2O2has different effect on the hemoglobin release of RBC.
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In order to study the effect of hydrogen peroxide(H2O2)on the hemoglobin release of normal human red blood cell(RBC),The malondialdehyde contents and relative solubility of RBC and hemoglobin release test(HRT)were used to study the hemoglobin release of normal RBCs treated with different concentration(8%,4%,2%,1%,0.5%,0.25%and 0.125%)of H2O2.The results show that the hemoglobin release was increased with increased concentration of H2O2.However,high concentration of H2O2could decrease the released Hb.So different concentrations of H2O2has different effect on the hemoglobin release of RBC.
Key concepts: Hemoglobin, Hydrogen peroxide, Chemistry, Malondialdehyde, Red blood cell, Solubility, Biochemistry, Oxidative stress