Toxicity of organophosphate insecticides to pyrethroid-resistant houseflies, Musca domestica vinica
Ying Jin, Guolei Feng
Abstract
Ying Jin, Guolei Feng
Abstract
The LD 50 ,α naphthylacetate(α NA)esterase kinetics,α,β NA esterase activity and IC 50 of dichlorvos(DDVP),phoxim and malathion to Del R、2Cl R and susceptible (SP) strains of houseflies were determined. The resistances of the Del R and 2Cl R to DDVP, phoxim and malathion were 0 966~7 190 folds as much as those of the SP strain,indicating a low resistance level to organophosphate insecticides in the pyrethroid resistant houseflies. An obvious correlation of the carboxylesterase activity with IC 50 suggested that the carboxylesterase would play a significant role in the resistance to organophosphates in pyrethroid resistant houseflies.
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The LD 50 ,α naphthylacetate(α NA)esterase kinetics,α,β NA esterase activity and IC 50 of dichlorvos(DDVP),phoxim and malathion to Del R、2Cl R and susceptible (SP) strains of houseflies were determined. The resistances of the Del R and 2Cl R to DDVP, phoxim and malathion were 0 966~7 190 folds as much as those of the SP strain,indicating a low resistance level to organophosphate insecticides in the pyrethroid resistant houseflies. An obvious correlation of the carboxylesterase activity with IC 50 suggested that the carboxylesterase would play a significant role in the resistance to organophosphates in pyrethroid resistant houseflies.
Key concepts: Phoxim, Malathion, Dichlorvos, Carboxylesterase, Organophosphate, Pyrethroid, Housefly, Toxicology