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Toxicity of organophosphate insecticides to pyrethroid-resistant houseflies, Musca domestica vinica

Ying Jin, Guolei Feng

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Abstract

The LD 50 ,α naphthylacetate(α NA)esterase kinetics,α,β NA esterase activity and IC 50 of dichlorvos(DDVP),phoxim and malathion to Del R、2Cl R and susceptible (SP) strains of houseflies were determined. The resistances of the Del R and 2Cl R to DDVP, phoxim and malathion were 0 966~7 190 folds as much as those of the SP strain,indicating a low resistance level to organophosphate insecticides in the pyrethroid resistant houseflies. An obvious correlation of the carboxylesterase activity with IC 50 suggested that the carboxylesterase would play a significant role in the resistance to organophosphates in pyrethroid resistant houseflies.

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The LD 50 ,α naphthylacetate(α NA)esterase kinetics,α,β NA esterase activity and IC 50 of dichlorvos(DDVP),phoxim and malathion to Del R、2Cl R and susceptible (SP) strains of houseflies were determined. The resistances of the Del R and 2Cl R to DDVP, phoxim and malathion were 0 966~7 190 folds as much as those of the SP strain,indicating a low resistance level to organophosphate insecticides in the pyrethroid resistant houseflies. An obvious correlation of the carboxylesterase activity with IC 50 suggested that the carboxylesterase would play a significant role in the resistance to organophosphates in pyrethroid resistant houseflies.

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Available abstract

The LD 50 ,α naphthylacetate(α NA)esterase kinetics,α,β NA esterase activity and IC 50 of dichlorvos(DDVP),phoxim and malathion to Del R、2Cl R and susceptible (SP) strains of houseflies were determined. The resistances of the Del R and 2Cl R to DDVP, phoxim and malathion were 0 966~7 190 folds as much as those of the SP strain,indicating a low resistance level to organophosphate insecticides in the pyrethroid resistant houseflies. An obvious correlation of the carboxylesterase activity with IC 50 suggested that the carboxylesterase would play a significant role in the resistance to organophosphates in pyrethroid resistant houseflies.

Key concepts: Phoxim, Malathion, Dichlorvos, Carboxylesterase, Organophosphate, Pyrethroid, Housefly, Toxicology

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Toxicity of organophosphate insecticides to pyrethroid-resistant houseflies, Musca domestica vinica — Research Paper | ScholarLens