ScholarLens Back to search
2014•Chinese Journal of Analysis LaboratoryRequires access

Development of a dispersive liquid-liquid microextraction method for the determination of sulfonamide residues in water samples by high performance liquid chromatography

Jin Zhang

Open publisher page 1 citations

Abstract

A novel method for the determination of sulfanilamide( SAD),sulfadiazine( SDZ) and sulfamethazine( SM2) residues in water samples has been developed by using dispersive liquid-liquid microextraction( DLLME)coupled with high performance liquid chromatography with DAD detection. Parameters such as type and volume of extraction solvent and disperser solvent,concentration and composition of sodium chloride and pH were optimized. The analytes were extracted under optimized pretreatment conditions. Linearity in the concentration range of 1 ~ 1000 μg /L was obtained with regression coefficients ranging from 0. 9997 to 0. 9999 and LODs were between 0. 07 and 0. 25 μg /L. The developed method was applied to the determination of the sulfonamides in five different water samples. The spiked recoveries were from 82. 0% to 104. 0% and the relative standard deviation( RSD) was less than 5. 9%( n = 6).

About this research paper

What this paper is about

A novel method for the determination of sulfanilamide( SAD),sulfadiazine( SDZ) and sulfamethazine( SM2) residues in water samples has been developed by using dispersive liquid-liquid microextraction( DLLME)coupled with high performance liquid chromatography with DAD detection. Parameters such as type and volume of extraction solvent and disperser solvent,concentration and composition of sodium chloride and pH were optimized. The analytes were extracted under optimized pretreatment conditions. Linearity in the concentration range of 1 ~ 1000 μg /L was obtained with regression coefficients ranging from 0. 9997 to 0. 9999 and LODs were between 0. 07 and 0. 25 μg /L. The developed method was applied to the determination of the sulfonamides in five different water samples. The spiked recoveries were from 82. 0% to 104. 0% and the relative standard deviation( RSD) was less than 5. 9%( n = 6).

Why it matters

OpenAlex reports 1 citations for this work. Citation counts describe recorded attention and do not establish research quality.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

A novel method for the determination of sulfanilamide( SAD),sulfadiazine( SDZ) and sulfamethazine( SM2) residues in water samples has been developed by using dispersive liquid-liquid microextraction( DLLME)coupled with high performance liquid chromatography with DAD detection. Parameters such as type and volume of extraction solvent and disperser solvent,concentration and composition of sodium chloride and pH were optimized. The analytes were extracted under optimized pretreatment conditions. Linearity in the concentration range of 1 ~ 1000 μg /L was obtained with regression coefficients ranging from 0. 9997 to 0. 9999 and LODs were between 0. 07 and 0. 25 μg /L. The developed method was applied to the determination of the sulfonamides in five different water samples. The spiked recoveries were from 82. 0% to 104. 0% and the relative standard deviation( RSD) was less than 5. 9%( n = 6).

Key concepts: Chemistry, Chromatography, Disperser, Solvent, Extraction (chemistry), Analyte, Sulfadiazine, Sulfanilamide

Related papers

Related paper 1Related paper 2Related paper 3
Back to paper searchBrowse research topicsOriginal source
Development of a dispersive liquid-liquid microextraction method for the determination of sulfonamide residues in water samples by high performance liquid chromatography — Research Paper | ScholarLens