Clinical implication of precordial ST segment depression in patients with acute inferior myocardial infarction

AIM:To investigate the relationship between coronary lesion characteristics and precordial ST segment depression and its clinical implication in patients with acute inferior myocardial infarction(AIMI).METHODS:Ninety one patients with the first AIMI were divided into four groups on the basis of admission electrocardiograms:Group I—patients with no precordial ST segment depression(n=27),Group II—patients with ST segment depression in leads V1 to V4(n=26),Group III—patients with ST segment depression in leads V5-V6(n=12)and Group IV of patients with ST segment depression in leads V1-V6(n=26).RESULTS:V1-V4 ST segment depression in AIMI was negatively correlated with multivessel lesion(ORIII=0.38,P0.05),whereas V1-V6 ST segment depression in AIMI was positively correlated with multivessel lesion(ORIV=5.25,P0.01)and lower left ventricular ejection fraction(P0.01).CONCLUSION:V1-V6 ST segment depression in AIMI suggests higher incidence of multivessel lesion and heart failure.