Study on the relationship between uric acid and insulin resistance in patients with gestational diabetes mellitus

Objective To study related index of patients with gestational diabetes mellitus, and explore the relationship between hyperuricemia and insulin resistance during pregnancy in the diabetic population.Methods A retrospective analysis was made of related indexes(plasma uric acid,insulin,insulin resistance)58 patients with gestational diabetes who were compared with 59 normal pregnant women.Results Fasting blood glucose,uric acid,insulin,and insulin resistance index of the gestational diabetes mellitus group and the control group were statistical different(P 0.05).Gestational diabetes mellitus group was higherin diabetes.The difference of uric acid in normal group and the high uric acid group in fasting blood glucose,uric acid,insulin,insulin resistance index pregnancy also had significant significance(P0.05 orP0.01),with high uric acid group being higher.Correlation analysis of UA associated with insulin was positive(r=0.675,P0. 05),and insulin resistance index of UA was positively correlated(r=0.606,P0.05).Conclusion There is a strong correlation between uric acid and insulin resistance in diabetic patients with high level of serum uric acid in pregnant patients,and pregnancy can to some extent reflect the level of insulin resistance,and can be used as the monitoring index of gestational diabetes mellitus treatment of attention.