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[The diagnosis and treatment of hypothalamic hamartoma in children].

S Luo, Li C, Zhong-fu Ma

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Abstract

OBJECTIVE: To investigate the diagnosis and treatment of hypothalamic hamartoma in children. METHODS: Eighteen cases of hypothalamic hamartoma in children, including 9 boys and 9 girls, were examined with CT and MRI. Eleven cases underwent operation. Post-operation follow-up was conducted for 0.5 approximately 6 years. RESULTS: The main clinical features of hypothalamic hamartoma were precocious puberty and gelastic seizures, some combine with other kinds of seizures, mental retardation or congenital abnormalities. The effective rate of surgery was 91%; patients with simple precocious puberty were cured. CONCLUSION: Microsurgery is the first choice of treatment for hypothalamic hamartoma.

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What this paper is about

OBJECTIVE: To investigate the diagnosis and treatment of hypothalamic hamartoma in children. METHODS: Eighteen cases of hypothalamic hamartoma in children, including 9 boys and 9 girls, were examined with CT and MRI. Eleven cases underwent operation. Post-operation follow-up was conducted for 0.5 approximately 6 years. RESULTS: The main clinical features of hypothalamic hamartoma were precocious puberty and gelastic seizures, some combine with other kinds of seizures, mental retardation or congenital abnormalities. The effective rate of surgery was 91%; patients with simple precocious puberty were cured. CONCLUSION: Microsurgery is the first choice of treatment for hypothalamic hamartoma.

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Available abstract

OBJECTIVE: To investigate the diagnosis and treatment of hypothalamic hamartoma in children. METHODS: Eighteen cases of hypothalamic hamartoma in children, including 9 boys and 9 girls, were examined with CT and MRI. Eleven cases underwent operation. Post-operation follow-up was conducted for 0.5 approximately 6 years. RESULTS: The main clinical features of hypothalamic hamartoma were precocious puberty and gelastic seizures, some combine with other kinds of seizures, mental retardation or congenital abnormalities. The effective rate of surgery was 91%; patients with simple precocious puberty were cured. CONCLUSION: Microsurgery is the first choice of treatment for hypothalamic hamartoma.

Key concepts: Hypothalamic hamartoma, Gelastic seizure, Precocious puberty, Hamartoma, Medicine, Pediatrics, Microsurgery, Surgery

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