Clinical and Pathological Analyses in Nephrotic Syndrome of Elder

Objective: To understand the nephrotic syndrome in the elderly.Methods: Clicinal and pathological analyses were performed in 34 patients with nephrotic syndrome, whose age were over 60. Results: 34 cases of nephrotic syndrome were diagnosed in the elderly. Among them, 23 cases(67.6%) had chronic glomerulonephitis, 6 cases(17.6%) had diabetic nephropathy.The clinical features presented little difference from those of younger patients, although 35.3% of the patients manifested anemia, 17.6% displayed chronic renal insufficiency. Membranous nephropathy was the particularly common type in biopsy. Damsge to the intertitium in the kidey was often observed. Steroid and immunosuppressive agent were effective, with the relief rate of 52.9%, the effectiv rate of 26.5% and the uneffective rate 20.6%. Conclusions: The nephrotic syndrome in elderly patients was not common and the clinical features differ little from those of younger patients, although complicated anemia, chronic renal insufficiency were more common than those in the young. The ratio of infection were higher than that in their younger counterparts.Chronic glomerulonephritis was the most common cause of the nephrotic syndrome in the elderly, Membranous nephropathy was particularly common in pathological detection. Nephrotic syndrome in the elderly responded well to corticosteroids and immunosuppressive agents.