ScholarLens Back to search
2014•New MedicineOpen access

CXC chemokine ligand 10 and cardiovascular diseases

Xiao Ming Shu

Open full text 0 citations

Abstract

CXC chemokine ligand 10( CXCL10),also known as interferon-inducible protein-10( IP-10),is a small chemokine belonging to the non-ELR-CXC chemokine family,which plays a pivotal role in leukocyte trafficking and cellular and tissue functions,such as endothelial and vascular smooth muscle cells. CXCL10 is able to regulate a cascade of inflammatory responses by binding to specific CXCR3 receptor,regarded as vital manifestations in cardiovascular diseases( CVD). The purpose of this review is to describe the functions of CXCL10 in different CVDs and discuss the possibility of utilizing CXCL10 as a potential biomarker in CVD study pattern.

About this research paper

What this paper is about

CXC chemokine ligand 10( CXCL10),also known as interferon-inducible protein-10( IP-10),is a small chemokine belonging to the non-ELR-CXC chemokine family,which plays a pivotal role in leukocyte trafficking and cellular and tissue functions,such as endothelial and vascular smooth muscle cells. CXCL10 is able to regulate a cascade of inflammatory responses by binding to specific CXCR3 receptor,regarded as vital manifestations in cardiovascular diseases( CVD). The purpose of this review is to describe the functions of CXCL10 in different CVDs and discuss the possibility of utilizing CXCL10 as a potential biomarker in CVD study pattern.

Why it matters

A significance statement is not available in the OpenAlex record.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

CXC chemokine ligand 10( CXCL10),also known as interferon-inducible protein-10( IP-10),is a small chemokine belonging to the non-ELR-CXC chemokine family,which plays a pivotal role in leukocyte trafficking and cellular and tissue functions,such as endothelial and vascular smooth muscle cells. CXCL10 is able to regulate a cascade of inflammatory responses by binding to specific CXCR3 receptor,regarded as vital manifestations in cardiovascular diseases( CVD). The purpose of this review is to describe the functions of CXCL10 in different CVDs and discuss the possibility of utilizing CXCL10 as a potential biomarker in CVD study pattern.

Key concepts: CXCL10, CXCR3, CXC chemokine receptors, CXCL9, CXCL16, Medicine, Chemokine, CXCL2

Related papers

Related paper 1Related paper 2Related paper 3
Back to paper searchBrowse research topicsOriginal source
CXC chemokine ligand 10 and cardiovascular diseases — Research Paper | ScholarLens