Analysis of wavefront aberration in myopic eyes

Objective To analyse the characteristics of wavefront aberrations in undilated,unoperated myopia eyes and investigate the value of application of wavefront aberrations.Design Retrospective case series.Participants 119 cases(238 eyes) of myopia subjects.Methods 238 eyes underwent wavefront aberrations examination using Nidek OPD-Scan ARK 10000.RMS values and figures of higher-order aberrations were obtained.Main Outcome Measures RMS values of five or less order aberrations.Results RMS values presented the degressive trend from lower-order to higher-order;there was statistically significant difference in different spherical equivalent refraction with lower-order,total higher-order or 3rd order wavefront aberrations;there is negative correlation between uncorrected visual acuity and lower-order aberrations;spherical equivalent refraction had the positive correlation with lower-order wavefront aberrations,also with total higher-order and with 3rd order aberrations;figures of higher-order were mainly trifoliate.Conclusions Wavefront aberrations in myopia eyes are mainly the loworder aberrations,total higher-order and 3rd order aberrations.Figures of higher-order aberrations have individual variance.Wavefront aberrations can accurately reveal the refractive posture of human eye and exactly guide the customized ablation of corneal refractive surgery.