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2009•Strait Pharmaceutical JournalRequires access

Bacterial endotoxin test for Honghuahuangsesu injection

KE Zheng-fang

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Abstract

OBJECTIVE To establish a method for the determination of bacterial endotoxin for Honghuahuangsesu injection.METHODS According to the method of determination of bacterial endotoxin approved by Chinese Pharmacopoeia 2005 edition.RESULTS The interference on the determination of bacterial endotoxin can be excluded when Honghuahuangsesu injection was diluted 300 times.CONCLUSION It is feasible to detect the bacterial endotoxin for Honghuahuangsesu injection by the method of determination of bacterial endotoxin and the method may replace pyrogen test.

About this research paper

What this paper is about

OBJECTIVE To establish a method for the determination of bacterial endotoxin for Honghuahuangsesu injection.METHODS According to the method of determination of bacterial endotoxin approved by Chinese Pharmacopoeia 2005 edition.RESULTS The interference on the determination of bacterial endotoxin can be excluded when Honghuahuangsesu injection was diluted 300 times.CONCLUSION It is feasible to detect the bacterial endotoxin for Honghuahuangsesu injection by the method of determination of bacterial endotoxin and the method may replace pyrogen test.

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Available abstract

OBJECTIVE To establish a method for the determination of bacterial endotoxin for Honghuahuangsesu injection.METHODS According to the method of determination of bacterial endotoxin approved by Chinese Pharmacopoeia 2005 edition.RESULTS The interference on the determination of bacterial endotoxin can be excluded when Honghuahuangsesu injection was diluted 300 times.CONCLUSION It is feasible to detect the bacterial endotoxin for Honghuahuangsesu injection by the method of determination of bacterial endotoxin and the method may replace pyrogen test.

Key concepts: Chromatography, Chemistry, Pharmacology, Medicine

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