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2006•Military Medical Journal of South ChinaRequires access

Study of Inhibitory Effects of Thirteen Kinds of Chinese Herbal Medicines on N.gonorrhoeae in Vitro

Xie Shou-zhen

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Abstract

Objiective To explore the inhibitory effects of 13 kinds of Chinese herbal medicines on N.gonorrhoeae in vitro. Methods The thirteen kinds of Chinese herbal medicines mainly inclnded Eugenia caryophyllata Thunb,Coptis chinensis Franch,Polygonum cuspidatum. et Zucc,Rhus chinensis Mill,Agrimonia pilosa Ledeb,Pulsatilla chinensis(Bge.)Regel and so on. The ethnal extrac was made from each of thirteen kinds of Chinese herbal medicines and diluted to different concentrations . Then their bacteriostasis were observed and minimum concentration (MIC) of inhibition of N.gonorrhoeae was determined. Results The MIC of Coptis chinensis Franch was 6.25mg/ml; The MIC of Pericarpium granati and Polygonum cuspidatum. et Zucc was 12.5mg/ml; The MIC of Phellodendron chinese Schneid 、Eugenia caryophyllata Thunb and Rhus chinensis Mill was 25mg/ml.The MIC of Sophrra flavescens Ait was 100mg/ml.Conclusions Coptis chinensis Franch,Pericarpium granati, Polygonum cuspidatum. et Zucc ,Phellodendron chinese Schneid,Eugenia caryophyllata Thunb and Rhus chinensis Mill have strong inhibitory effects on N.gonorrhoeae in vitro.The Coptis Chinensis Franch has the strongest effect on N.gonorrhoeae in 13 kids of Chinese herbal medicines.

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Objiective To explore the inhibitory effects of 13 kinds of Chinese herbal medicines on N.gonorrhoeae in vitro. Methods The thirteen kinds of Chinese herbal medicines mainly inclnded Eugenia caryophyllata Thunb,Coptis chinensis Franch,Polygonum cuspidatum. et Zucc,Rhus chinensis Mill,Agrimonia pilosa Ledeb,Pulsatilla chinensis(Bge.)Regel and so on. The ethnal extrac was made from each of thirteen kinds of Chinese herbal medicines and diluted to different concentrations . Then their bacteriostasis were observed and minimum concentration (MIC) of inhibition of N.gonorrhoeae was determined. Results The MIC of Coptis chinensis Franch was 6.25mg/ml; The MIC of Pericarpium granati and Polygonum cuspidatum. et Zucc was 12.5mg/ml; The MIC of Phellodendron chinese Schneid 、Eugenia caryophyllata Thunb and Rhus chinensis Mill was 25mg/ml.The MIC of Sophrra flavescens Ait was 100mg/ml.Conclusions Coptis chinensis Franch,Pericarpium granati, Polygonum cuspidatum. et Zucc ,Phellodendron chinese Schneid,Eugenia caryophyllata Thunb and Rhus chinensis Mill have strong inhibitory effects on N.gonorrhoeae in vitro.The Coptis Chinensis Franch has the strongest effect on N.gonorrhoeae in 13 kids of Chinese herbal medicines.

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Available abstract

Objiective To explore the inhibitory effects of 13 kinds of Chinese herbal medicines on N.gonorrhoeae in vitro. Methods The thirteen kinds of Chinese herbal medicines mainly inclnded Eugenia caryophyllata Thunb,Coptis chinensis Franch,Polygonum cuspidatum. et Zucc,Rhus chinensis Mill,Agrimonia pilosa Ledeb,Pulsatilla chinensis(Bge.)Regel and so on. The ethnal extrac was made from each of thirteen kinds of Chinese herbal medicines and diluted to different concentrations . Then their bacteriostasis were observed and minimum concentration (MIC) of inhibition of N.gonorrhoeae was determined. Results The MIC of Coptis chinensis Franch was 6.25mg/ml; The MIC of Pericarpium granati and Polygonum cuspidatum. et Zucc was 12.5mg/ml; The MIC of Phellodendron chinese Schneid 、Eugenia caryophyllata Thunb and Rhus chinensis Mill was 25mg/ml.The MIC of Sophrra flavescens Ait was 100mg/ml.Conclusions Coptis chinensis Franch,Pericarpium granati, Polygonum cuspidatum. et Zucc ,Phellodendron chinese Schneid,Eugenia caryophyllata Thunb and Rhus chinensis Mill have strong inhibitory effects on N.gonorrhoeae in vitro.The Coptis Chinensis Franch has the strongest effect on N.gonorrhoeae in 13 kids of Chinese herbal medicines.

Key concepts: Coptis chinensis, Traditional medicine, Coptis, Polygonum, Minimum inhibitory concentration, Medicine, In vitro, Biology

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