Synthesis of N-phenylphthalimide with Using β-Cyclodextrin as Catalyst

N-phenylphthalimide was synthesized with using aniline and phthalic anhydride as raw materials and β-cyclodextrin as catalyst in the presence of hydro-solvent.The effects of reaction time,catalyst amount,ratio of aniline to phthalic anhydride and solvent amount on the production yield were investigated.The results showed that the β-cyclodextrin had excellent catalytic activity,and the optimum reaction conditions were as follows: the molar ratio of aniline to phthalic anhydride was 1:1.3,the amount of hydro-solvent with a small dosage of hydrochloric acid was 30mL,the reaction time was 5h and the amount of catalyst was 1%(mass) of solvent;the yield of product was up to 88.7%,and the stability of reused catalyst was excellent.