The Progress in the Research of GCLE as a Reactive Intermediate for Cephalosporin Antibiotics
Yang Li
Abstract
Yang Li
Abstract
Three synthetic methods as well as characteristic features of 3-chloromethyl-△~3-cephem(GCLE), a new reactive intermediate for the synthesis of a wide variety of antibiotics of cephalosporin, are described.The synthetic utility of GCLE are also described.
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Three synthetic methods as well as characteristic features of 3-chloromethyl-△~3-cephem(GCLE), a new reactive intermediate for the synthesis of a wide variety of antibiotics of cephalosporin, are described.The synthetic utility of GCLE are also described.
Key concepts: Cephalosporin Antibiotic, Chemistry, Cephalosporin, Cephem, Antibiotics, Combinatorial chemistry, Organic chemistry, Biochemistry